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January 1, 2011

Fermentation Process Development

Today’s development depends on synthetic biology and efficient screening

The range of synthetic biology tools available for manipulating microbial metabolic pathways has expanded significantly in the past decade, opening new routes to chemical products. But the development challenges associated with strain development, as well as scaling up effective fermentation processes remain. Companies manufacturing biofuels, bio-based chemical intermediates, natural products and therapeutic proteins, are all capitalizing on powerful synthetic biology techniques to rationally engineer microbes, as well as seeking ways to use high-throughput screening systems that will expedite the development of robust and efficient cellular-production platforms and the effectiveness of process development and scaleup...

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