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Optimizing Analysis for Spray-Drying

By Daisuke Sasakura, Malvern Instruments and others |

Precise control over spray-drying processes can be enabled by modern measurement approaches that provide information on particle size and shape in realtime The process of spray drying is extremely valuable to a wide range of solid-product manufacturers due to its ability to produce particles with precisely controlled size and shape. Cutting-edge spray drying technology is used in industries ranging from food and pharmaceuticals, to industrial materials, metal powders and chemicals. Spray drying technology is typically selected for its ability to deliver standardized particles, so optimizing analytical strategies for process monitoring is crucial to its successful implementation. Methods for monitoring spray drying have developed significantly in recent years, with new technologies making it easier to achieve precise control. In this article, we look at those techniques that are proving particularly valuable, focusing on online particle sizing and automated imaging, a technology that quantifies particle shape, as well as size. Spray drying advantages Spray drying produces a dry powder from a liquid solution or slurry. The liquid is sprayed into a drying chamber in which air, or an inert gas, drives off the solvent to leave a dried…
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