Processing & Handling :: Liquid, Gas and Air Handling :: Mixing
March 1, 2014
Mass Transfer in Fermentation Scaleup
As fermenters are scaled up to huge sizes, mass transfer is a key consideration
Jim Gregory and Bob Green, Fluor;
Nicolle Courtemanche and Richard Kehn, SPX Flow Technology, Lightnin
How big can a fermenter get? And what would the biggest fermenter look like? The answers to these questions depend upon how the requirements of heat transfer, mass transfer (gas-to-liquid), and momentum transfer (mixing) are met. This article examines the issues that arise with mass and momentum transfer at huge scales. The concerns associated with mass transfer at huge scales also influence the type and size of pilot- and demonstration-plant facilities that are used in scaleup....
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