Comment PDF Processing & Handling
A new catalyst for C-C and crossed-coupling
By Tetsuo Satoh |
Tokyo Chemical Industry Co. (TCI; Tokyo; www.tokyokasei.co.jp) is planning full-scale production of a new palladium-complex catalyst, trade-named SingaCycle-E1, for performing Heck-Mizoroki carbon-carbon coupling reactions and the Suzuki-Miyaura cross-coupling reaction — both reactions of importance for producing pharmaceuticals. TCI says SingaCycle-E1 offers enhanced activity and improved stability over conventional catalysts used for such reactions, and believes the catalyst may also be used for electronic materials.
Developed in collaboration with the National Public Research Institute of Singapore (www.nus.edu.sg), SingaCycle-E1 — Chloro[(1,3-dimesitylimidazol-2-ylidene)( N,N -dimethylbenzylamine)palladium(II)] — has two ligands. One is N -hetero cyclic carbene (NHC), a highly-active and robust ligand widely used in the cross-coupling reactions. The other is a palladacycle ligand containing an elimination unit formed when the catalyst is activated. The catalyst performance is optimized by adjusting the combination of NHC ligand and the ligand to be eliminated from palladacycle.
The company says the catalyst is stable and easy to handle in atmospheric condition, and could be used over a wide range of scales, from…
Related Content The following is a list of recently published books that may be relevant for professionals in the chemical process industries…
In a variety of industrial applications, crystallization technologies contribute to the circularity of manufacturing processes and supply chains Crystallization is…
Thermal oxidizers are pollution-control units designed to prevent process-generated volatile organic compounds (VOCs) from entering the environment. Different technologies offer…
This column is based on “Acrylonitrile Butadiene Latex Production – Cost Analysis,” a report published by Intratec. It can be…
This column is based on “Butyl Acrylate Production from Acrylic Acid and Butanol – Cost Analysis,” a report published by…
Breakthrough Technologies
Chemical Engineering publishes FREE eletters that bring our original content to our readers
in an easily accessible email format about once a week.
Subscribe Now
Subscribe Now
Job Listings