I D
× COMMENTARYCOVER STORYIN THE NEWSNEWSFRONTSCHEMENTATOR + Show More
Chemical Engineering MagazineChementator Briefs
PDH catalyst Last month, Clariant's Catalyst business (Munich, Germany; www.clariant.com)…
BUSINESS NEWSTECHNICAL & PRACTICALFEATURE REPORTFACTS AT YOUR FINGERTIPSTECHNOLOGY PROFILESOLIDS PROCESSINGENGINEERING PRACTICEEQUIPMENT & SERVICESFOCUS
Focus on Pumps
Self-priming, liquid-ring pumps enable hygienic operation The CFS AS/ASH Series…
NEW PRODUCTS + Show More

Comment

Control particle size and morphology with this technique

By Paul Grad |

Lactose has been widely used as a pharmaceutical excipient, where the size and morphology of the particles of lactose significantly affect the functionality of the resultant drug product. Lactose particles produced by various methods exhibit various morphologies, such as spherical amorphous particles, or lactose crystals with tomahawk or sharp and fine morphology. To date, however, there is no report in which a single process can be manipulated to produce both types of morphology, according to a team from Monash University (Melbourne, Australia; www.monash.edu.au). Together with colleagues from Xiamen University (Xiamen) and Soochow University (Suzhou, both China), the team has developed a technique, called antisolvent vapor precipitation (AVP), which can be controlled to produce ultra-fine lactose particles of uniform size, with spiky crystalline morphology or spherical amorphous morphology. The method is expected to improve the efficiency of powder pulmonary-drug delivery, as for example in the case of asthma inhalers. With current inhaler designs, a large portion of medication propelled into a patient’s throat remains there, and only a fraction reaches the lower regions of the lungs, says team member Meng Wai Woo, of Monash’s…
Related Content
Removing PFAS from wastewater
A new low-cost, safe and environmentally friendly method for removing polyfluorinated alkyl substances (PFAS) from water has been developed by…
A sound way to make MOFs
Researchers from RMIT University (Melbourne, Australia; www.rmit.edu.au) have demonstrated a “green” technique that can produce customized metal organic framework (MOF)…
Chementator Briefs
PDH catalyst Last month, Clariant's Catalyst business (Munich, Germany; www.clariant.com) launched its latest propane dehydrogenation (PDH) catalyst, Catofin 311, which…

Chemical Engineering publishes FREE eletters that bring our original content to our readers in an easily accessible email format about once a week.
Subscribe Now
Quadruple Sensor Lifetime with a Retractable Housing
Minimizing Explosion Risk Where Other Solutions Cannot
Minimizing Corrosion with Fast, Robust Gas Analysis
Lower Measurement Point Costs with Automatic pH Sensor Cleaning
Reduce the Risk of Corrosion in Fertilizer Production

View More

Live chat by BoldChat