I D
× COMMENTARYCOVER STORYIN THE NEWSNEWSFRONTSCHEMENTATOR + Show More
Chemical Engineering MagazineChementator Briefs
PDH catalyst Last month, Clariant's Catalyst business (Munich, Germany; www.clariant.com)…
BUSINESS NEWSTECHNICAL & PRACTICALFEATURE REPORTFACTS AT YOUR FINGERTIPSTECHNOLOGY PROFILESOLIDS PROCESSINGENGINEERING PRACTICEEQUIPMENT & SERVICESFOCUS
Focus on Pumps
Self-priming, liquid-ring pumps enable hygienic operation The CFS AS/ASH Series…
NEW PRODUCTS + Show More

Comment

A step forward for bio-based butadiene

By Scott Jenkins |

Increased use of ethane from shale deposits as a feedstock for ethylene production has focused attention on the growing need for on-purpose production of butadiene, which has traditionally been produced primarily as a byproduct of conventional ethylene production from naphtha. Among the areas of exploration has been a bio-based route to butadiene using renewable feedstock. Now, a joint effort by Genomatica (San Diego, Calif.; www.genomatica.com) and Braskem (São Paulo, Brazil; www.braskem.com) has resulted in the continuous, direct production of butadiene from sugar using a fermentation-based process. The companies say that their technology platform is “running well” and they have been producing bio-based butadiene at laboratory scale since June 2015. The Genomatica-Braskem program has developed a bacterial strain capable of consuming sugar and synthesizing butadiene in 2-L fermenters. Using computational tools, Genomatica identified 60 possible metabolic routes to butadiene and selected the five most promising — in terms of enzyme activity and specificity, as well as favorable free energies — for experimental validation. With genetic engineering, enzyme modification and directed-evolution on the relevant metabolic pathway,…
Related Content

Chemical Engineering publishes FREE eletters that bring our original content to our readers in an easily accessible email format about once a week.
Subscribe Now
Quadruple Sensor Lifetime with a Retractable Housing
Minimizing Explosion Risk Where Other Solutions Cannot
Minimizing Corrosion with Fast, Robust Gas Analysis
Lower Measurement Point Costs with Automatic pH Sensor Cleaning
Reduce the Risk of Corrosion in Fertilizer Production

View More

Live chat by BoldChat