I D
× COMMENTARYIN THE NEWSNEWSFRONTSCHEMENTATOR + Show More BUSINESS NEWSTECHNICAL & PRACTICALFEATURE REPORTFACTS AT YOUR FINGERTIPSTECHNOLOGY PROFILEENVIRONMENTAL MANAGEREQUIPMENT & SERVICESFOCUSNEW PRODUCTS + Show More

Comment

A step forward for bio-based butadiene

By Scott Jenkins |

Increased use of ethane from shale deposits as a feedstock for ethylene production has focused attention on the growing need for on-purpose production of butadiene, which has traditionally been produced primarily as a byproduct of conventional ethylene production from naphtha. Among the areas of exploration has been a bio-based route to butadiene using renewable feedstock. Now, a joint effort by Genomatica (San Diego, Calif.; www.genomatica.com) and Braskem (São Paulo, Brazil; www.braskem.com) has resulted in the continuous, direct production of butadiene from sugar using a fermentation-based process. The companies say that their technology platform is “running well” and they have been producing bio-based butadiene at laboratory scale since June 2015. The Genomatica-Braskem program has developed a bacterial strain capable of consuming sugar and synthesizing butadiene in 2-L fermenters. Using computational tools, Genomatica identified 60 possible metabolic routes to butadiene and selected the five most promising — in terms of enzyme activity and specificity, as well as favorable free energies — for experimental validation. With genetic engineering, enzyme modification and directed-evolution on the relevant metabolic pathway,…
Related Content
The New Era of Sustainable Supply Chains
To improve sustainability, materials manufacturers are welcoming new digital technologies and process innovations into their global supply chains From palm…

Chemical Engineering publishes FREE eletters that bring our original content to our readers in an easily accessible email format about once a week.
Subscribe Now
Improving chemical production processes with IIoT and AI technologies
New filtration technology for highly corrosive media
PTA production: Lowering OPEX without compromising on quality
Sure that zero means zero in your zero-liquid discharge (ZLD) process?
How separation processes profit from Industrial Internet of Things (IIoT) solutions

View More

Live chat by BoldChat