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Hot-melt coating for pharma applications

By Gerald Ondrey |

Polymer coatings are often used to mask the taste of pharmaceuticals, as well as to serve as moisture barriers to granules or tablets. However, the application of polymer solutions requires considerable time and energy for drying after the coating has been applied. Processing times can now be shortened by up to 85% using a hot-melt coating technology developed by Romaco Innojet GmbH (Steinen, Germany; www.romanco.com). The company’s IHD series was specially designed for coating and granulating pharmaceutical products with hot greases and waxes, which simply harden when cooled, thereby eliminating the time and energy needed for drying. Speaking at a pre-Achema press event at Dechema (Frankfurt am Main, Germany) last month, technology director Kai Koch presented an example of the coating of 1 kg of granulate. Whereas the conventional process of coating with a polymer solution 500 g polymer in 2,833 g of water requires 278 minutes of processing time to form the coated granulate, the hot-melt coating of 500 g onto the same granulate required only 42 minutes. Although the technology has been used in other sectors, the company has now launched a system that is compliant with Good Manufacturing Practice (GMP), specifically for pharmaceutical…
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