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Technical & Practical

FDA Form 483: Minimizing FDA Inspection Citations

As an owner or manager of a company whose product is regulated by the U.S. Food and Drug Administration (FDA), you will, at some point, be subjected to an FDA inspection. And once an inspection is underway in your facility,…

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Methanol-to-Olefins Process

Ethylene and propylene are the most important intermediates in the petrochemical industry. Globally, they are produced mainly by steam cracking of hydrocarbons, such as naphtha, propane and ethane. The methanol-to-olefins (MTO) process is an alternative approach to producing these light…

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Implementing a Corrosion-Under-Insulation Program

Corrosion to the external surface of process piping and vessels that is hidden under the insulation is referred to as corrosion under insulation (CUI). Aging piping and equipment in chemical plants and petroleum refineries have made CUI detection and assessment…

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Polypropylene Production via Gas-Phase Process: Stirred-bed reactor

Since 1956, polypropylene has been commercially produced using catalysts and technology that were developed from independent research by Karl Ziegler and Giulio Natta. Their namesake catalysts have enabled the widespread use of this polymer in the decades since. Polypropylene has…

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Compressible Fluid Flow Calculation Methods

Compressible gas flow with significant variation in density along pipes is commonplace in the chemical processing industries (CPI). In designing these pipes for compressible flow, it is important to calculate the pressure loss or maximum gas-handling capacity for safety and…

Chemical Protective Clothing

Workers in the chemical process industries (CPI) can wear chemical protective clothing to protect themselves from exposure to potentially hazardous chemicals in the form of vapor, liquid and solid particles. While chemical protective clothing has not been regulated to the…

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Quick Pipe and Duct Flow Calculations

Would you like to make a quick mental calculation to determine approximate flowrate, velocity, or pipe and duct sizes for many common situations? This article presents two methods for estimating flow characteristics without the aid of charts, tables, calculators or…

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Small-matrix, Model-less Multivariable Control

Beginning with the early days of automated multivariable control in the 1980s, the trend has always been toward the use of larger matrices and more models. Today’s multivariable controllers commonly comprise dozens of variables and hundreds of models. But the…

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Seven Tools for Project Success

Have you ever heard someone say, “The job is a lot easier if you have the right tools?” Having the right tools is critical to the success of craftsmen, such as carpenters, electricians, plumbers and the like. The same holds…

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Propylene Production via Propane Dehydrogenation

Propylene is the second most important intermediate in the petrochemical industry after ethylene, and its global demand is dominated by the production of polypropylene. However, the growing use of natural gas from shale deposits as a raw material for steam…