ID
× COMMENTARYCOVER STORYIN THE NEWSNEWSFRONTSCHEMENTATOR + Show More BUSINESS NEWSTECHNICAL & PRACTICALFEATURE REPORTFACTS AT YOUR FINGERTIPSTECHNOLOGY PROFILEENGINEERING PRACTICEEQUIPMENT & SERVICESFOCUSNEW PRODUCTS + Show More

Comment

Single-use perfusion system for cell culture process development

By Chemical Engineering |

Sartorius

Sartorius

Last month, this company launched the ambr 250 high-throughput (ht) perfusion (photo), a new automated parallel bioreactor system. It has been specially designed for rapid cell-culture-perfusion process development to optimize production of therapeutic antibodies. The ambr 250ht perfusion system was developed in collaboration with major biopharmaceutical companies. It combines 12 or 24 single-use perfusion mini bioreactors (100–250 mL working volume) with associated single-use perfusion components, all controlled by one automated workstation. The combination of this multi-parallel processing capacity and fully single-use perfusion vessel enables scientists to perform more perfusion culture experiments in a fraction of the time and cost of using traditional perfusion-enabled benchtop bioreactors. This new innovation supports a range of hollow-fiber perfusion applications, enabling design of experiments (DoE) studies for high-cell-density process development in a quality by design (QbD) approach. — Sartorius Stedim Biotech, Göttingen, Germany

www.sartorius.com

 

Related Content
Interphex 2018 Show Preview
Interphex, the annual event focused on pharmaceutical and biotechnology manufacturing, takes place April 17–19 at the Jacobs Javits Center in…

Chemical Engineering publishes FREE eletters that bring our original content to our readers in an easily accessible email format about once a week.
Subscribe Now
Non-Contacting Gas Sensors Minimize the Risk of Corrosion to Plant Equipment.
5 ways to Optimize Production of Polymers and Intermediate Petrochemicals
7 Ways to Achieve Process Safety in Chemical Production
Five Reasons Why Chemical Companies Are Switching to Tunable Diode Laser Analyzer Technology
Simplify sensor handling and maintenance with ISM

View More

Live chat by BoldChat