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A single flow reactor produces a toxic precursor, an unstable reagent and product

The Vilsmeier reagent (VR), [(CH3)2 NCHCl]Cl, is necessary for producing a large range of pharmaceuticals, but it is unstable in air and is made from the toxic precursor phosgene (COCl2). A new flow-reactor system has been developed by Akihiko Tsuda,…

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Safely Operating a Heat-Transfer-Fluid System

Being aware of and understanding potential hazards are crucial for operating a heat-transfer-fluid system safely A significant number of industrial processes require heating or cooling with precise temperature control. Maintaining this temperature control can be achieved through several industrial practices,…

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Modular Construction Encourages New Applications

The efficiency and cost effectiveness of modularity provides advantages for small- and large-scale projects When the right conditions exist, the benefits of modular construction — from laboratory scale to large scale — are plentiful and allow single-source, cost-effective and efficient…

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Precise degradation control is key to advanced bioresorbable polymers

Bioresorbable polymers — those that degrade naturally over time and can be absorbed by the body — are essential for delivering a number of advanced biomedical technologies to patients, including long-acting injectable or implanted products, regenerative scaffolds, degradable medical devices,…

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First-phase pilot tests completed to demonstrate RotoDynamic technology

Coolbrook Oy (Helsinki, Finland; www.coolbrook.com) has successfully completed the first phase of large-scale pilot testing (photo) for its RotoDynamic Technology at the Brightlands Chemelot Campus in Geleen, the Netherlands. During 2023, Coolbrook has been running a test program to demonstrate…

Solids Flow Measurement in Specialty Chemicals: Seamless Integration

Continuous flow measurement is used at this Austrian specialty chemicals manufacturer for process optimization, as well as overload protection Sensing-plate weighing systems are often used for weighing free-flowing and very dusty bulk materials. Such solids flowmeters ensure reliable determination of…

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Hydrogen Production via Methane Pyrolysis: An Overview of ‘Turquoise’ Hydrogen

‘Turquoise’ hydrogen processes generate H2 without releasing CO2. Presented here are the opportunities and challenges for producing hydrogen by methane pyrolysis Hydrogen-producing processes are classified using a color scheme according to their carbon footprint (Table 1; [1–3]). So-called “turquoise hydrogen”…

Management and Maintenance Strategies for Valves

Asset criticality and risk are primary among the many factors that must be considered to appropriately manage valves throughout their lifecycle Asset strategies usually define how assets will be treated in the different phases of an asset lifecycle, from acquisition…

Focus On Industrial Housekeeping

Customized wash racks ensure safe cleaning of labware A key option offered with this company’s automated cleaning and disinfecting wash systems, the custom wash rack services (photo) were developed to help pharmaceutical and nutritional-product manufacturers ensure complete cleaning and disinfection…

Clariant to acquire cosmetics business from IFF

Clariant AG (Muttenz, Switzerland) announced that it has agreed to acquire Lucas Meyer Cosmetics, a leading provider of high value ingredients for the cosmetics and personal care industry, from International Flavors & Fragrances (IFF) for a total cash consideration of…